HEPATONE

Hepatone

Trademark of Richmond Vet Pharma S.A.

Sorbitol Thiamine Thioctic acid DL Methionine

Veterinary Use

Hepatone. Protector and stimulant of the liver function. Ready to use sterile injectable solution

Composition

Sorbitol 21.00 g, DL methionine 1.50 g, Thiamine HCl 0.30 g, Thioctic acid 0.20 g, Excipients c.s.p. 100.00 mL.

Indications

Hepatone protects and stimulates liver activity, with increased glycogen reserve. It acts effectively in metabolic dysfunction favoring the normal functioning of the liver cell. It has antitoxic action.

Hepatone is indicated in hepatic dysfunctions such as hepatitis, liver failure, lead, mercury or arsenic poisoning. Food poisoning.  Ketosis.

Average Orientation Dosage

Apply intravenously or deep intramuscularly

Horses and Cattle:     50 to 100 mL total

Swine:                          10 a 20 mL

Sheep:                   5 a 10 mL

Dogs and Cats:                 1 mL every 10 kg of weight

Administer every 24 hours, for 5 days or until the values corresponding to the hepatogram are normal for each species.

Biodisponibility

Once injected parenterally, this solution is well tolerated by tissues due to its pH and composition which ensures total absorption of the compound.

Thiamine is activated after being absorbed; its active form is TPP (cocarboxylase), a coenzyme necessary for the oxidative decarboxylation of alfacetoacidosis.

Thiamine after activation acts on oxidative decarboxylation. From the metabolic point of view the critical or limiting enzymatic defect in thiamine deficiency is in the oxidative decarboxylation of pyruvic acid. This reaction is essential for the complete oxidation of glucose through the citric acid cycle. Tissues whose energy depends on glucose or lactate-pyruvate are especially compromised in the lack of thiamine.

Methionine, in addition to being the main donor of methyl groups in the body (yield it to ethanolamine to form choline), contains sulfur that protects the liver against the harmful actions of certain toxins.

Thioctic acid promotes liver function with increased glycogen reserve. It also acts as an antioxidant in numerous adverse or toxic reactions by drugs and xenobiotics and has a chelating action in heavy metal poisoning. Both thioctic acid and thiamine are essential for the normal performance of the Krebs cycle.

Precautions and Warnings

Verify that the product inviolability system and its storage condition prior to use are adequate, as well as that it has not expired in reference to the expiration date expressed on the label

Do not eat. Keep out of the reach of children and domestic animals.

In all cases, the doses and frequencies are at the discretion of the acting professional.

Storage

The appropriate temperature for the correct conservation of the product is between 15 and 30ºC, protected from direct sunlight, and kept in a dry and hygienic place.

Always consult your veterinarian.

Recyclable packaging. Destroy after use.

UNDER VETERINARY PRESCRIPTION ONLY

Hepatone 50, 100 y 250 mL | Vial

Multidose vial