ACUPRIN
Nutritional supplement for zinc and copper dependent imbalances. Ready to use sterile injectable emulsion.
COMPOSITION
Copper and Zinc Edetate 40.3 g; Dl Methionine 1.1 g; Agents and sterile purified water q.s.f. 100.00 mL.
INSTRUCTIONS FOR USE
Acuprin is indicated as curative and preventive of primary or secondary origin of deficiency states, with respect to Copper and/or Zinc, in cattle, sheep and swine.
Acuprin prevents and reverses pathophysiological diseases and metabolic imbalances such as:
- Nutritional Anestrus
- Deficiency infertility syndrome
- Abortions
- Placental retentions because of poor nutrition
- Embryonic Absorption
- Subclinical mastitis
- Cystic and polycystic ovaries
- Repeted heat
- Perinatal death
- Metritis
These are, among others, secondary relevance symptoms in the combined and manifest lack of Copper and/or Zinc in the diet.
Both copper and zinc are essential cofactors for the activation of important enzymes responsible for the initiation of intracellular specific metabolic functions.
Acuprin is indicated in lowlands and fields whose lands have an alkaline pH and/or its waters contain a high value of free or conjugated sulfates and/or presence of Molybdenum in the soil.
This two elements (Sulfates and Molybdenum), tend to chelate copper and zinc at plant level and/or intrarruminal level preventing one way or another to cover animals zinc and copper requirements for maintenance and production. This situation will lead the animal to a subclinical and/or clinical shortage with visible signs and symptoms. Examples of these symptoms and signs are hyperkera tosis or parakeratosis in cattle and swine with localized or diffuse hair removal and pruritus, achromatrichia (hair discoloration), anorexia, diarrhea and catharsis; until arriving at the anorexia and death of them. Other symptoms that demonstrate problems of keratinization or epithelial fragility are chronic pododermatitis or “canker” and insidius keratoconjunctivitis in cattle.
- Improves spermatogenesis in bulls, prevent osteomalacia and rickets.
- Promotes bone and muscle development and growth, increasing the animal’s cellular and humoral defenses, increasing food conversion by elevating production parameters.
Use in cattle, sheep and swine of any breed, age, sex and productive condition.
INDICATIVE DOSAGE
- Animals less than 200 kg: 2 mL total
- Animals over than 200 kg: 3 mL total
- Steer, heifers, bulls and cows: maximum 4 mL total
Application route: Exclusively Subcutaneusly.
This dosage should be respected for both curative and preventive treatments, regardless of the species, age, sex, breed and category of the animal or productive system.
STRATEGIC SUPPLEMENTATION
Females between 6 to 7 months of gestation (indicated to supplement fetal deficiencies)
Female postpartum (approximately 45 to 60 days postpartum) is indicated in order to restore blood levels prior to the next service.
In calves 2 to 3 months age before beginning their first grazing. Another dose should be repeated according to weight between 6 to 9 months of age.
SYSTEMATIC SUPPLEMENTATION
It may be applied systematically every 3 to 6 months in order to maintain serum copper and zinc levels in the rodeo.
In curative treatments of canker or in case of insidious keratoconjunctivitis, a dose of Acuprin can be use according to weight, repeating at 30 to 60 days.
Sheep:
It may be administered between 4 to 6 weeks prior to the estimated lambing date, repeating the copper treatment after parturition.
