Algen 20. Potent Somatic and Visceral Analgesic. Ready to use Injectable Sterile Solution.
A safe alternative in cardiac patients due to cardiovascular stability at the indicated doses.
Tramadol Hydrochloride 2.0 g; Excipients q.s.f. 100 mL.
Tramadol Hydrochloride is a synthetic derivative of codeine, µ agonist, used as an analgesic for a variety of acute and chronic pain syndromes.
Algen 20 has a dual mechanism of action, on one side it joins Mu-opioid receptors and on the other side it inhibits the reuptake of Noradrenaline and Serotonine, thereby increasing the activity of these neurotransmitters. This dual mode of action gives a powerful synergistic action, leading to a comparable analgesia with meperidine or codeine. Its duration of action is around 6-8 hours.
Algen 20 is indicated for moderate to severe somatic and / or visceral pain and for the control of acute or chronic pain (fractures, sprains, contusions, osteoarthritis, neuropathies, etc.).
Algen 20 can be administered during anesthetic premedication in order to improve intra-operative analgesia and provide the patient a comfortable awakening.
Algen 20 can be combined in an anesthetic protocol with tranquilizers and anticholinergics. Its combination with major tranquilizers increases the sedative action and justifies the dose reduction.
Algen 20 is used in the treatment of post surgical pain in outpatients and inpatients, appearing as an effective alternative in most abdominal surgeries, mastectomies, orthopedic and spine surgery.
The combination of Algen 20 with nonsteroidal antiinflammatory drugs, increases its effectiveness, producing a multimodal pain relief action.
Cats and Dogs
1 – 2 mg / kg; SC, IM, Slow IV, Epidural.
1 mg / kg; Slow IV Infusion, Epidural.
Interval between doses: administrate every 6 to 8 hours.
MAO inhibitors (selegiline) and inhibitors of cytochrome P450 (cimetidine, ketoconazole, erythromycin) can potentiate the toxicity of Tramadol by increasing its plasmatic concentration.
Its administration together with agonists / antagonists (for example buprenorfine, nalbufine) may reduce the analgesic effect.
When combined with α2 agonists, like xylazine or medetomidine, respiratory depression may be observed. In these cases, it is recommended to apply intramuscularly, reduce the final dose of α2 agonists and to consider the need to atropinise the patient.
Contraindications and Limitations of Use
Do not administrate in patients with prior history of hypersensitivity to the drug or severe hepatic or renal failure.
Do not use in pregnant or lactating females.
Do not administrate by rapid intravenous infusion or bolus.
It is contraindicated in patients with uncontrolled epilepsy.
It is contraindicated in the treatment of pain caused by pancreatitis.
Use with caution in patients who are treated with MAO inhibitors (selegiline) and cytochrome P450 inhibitors (cimetidine, ketoconazole, erythromycin) or patients who have received it in the course of the last two weeks, because they may potentiate the toxicity of Tramadol by increasing its plasmatic concentration.
Do not administrate together with agonists / antagonists (for example buprenorfine, nalbufine) because it may reduce the analgesic effect.
Under Veterinary Prescription Only
Store between 15 ºC and 30 ºC, protected from direct sunlight in a dry and hygienic place. Do not swallow. Keep out of reach of children and domestic animals. Always consult your Veterinarian.
Mon a Fri: 08:00-17:00
Where we are
Fragata Heroína 4988 (B1615ICH)
Grand Bourg, Buenos Aires, Argentina.